Codeage Methylfolate B-Complex +

What it's for

Energy metabolism support; Methylation and homocysteine support; Nervous system support

Who it may fit
Adults with busy lifestyles who want easy daily B-vitamin support, or individuals with low intake of B-rich foods.

Key actives per serving
Riboflavin-5'-phosphate (Vitamin B2): 30 mg (2308% DV)
Pyridoxal-5'-phosphate (Vitamin B6): 15 mg (882% DV)
5-Methyltetrahydrofolate (Quatrefolic): 1,360 mcg DFE (340% DV)
Methylcobalamin (Vitamin B12): 1,000 mcg (41667% DV)
Betaine (Trimethylglycine): 600 mg

How to take
Adults take 2 capsules once daily with 8 ounces of water; may be taken with or without food. If sensitive, try with a meal to improve comfort.

Diet / Allergen fit
Non-GMO; Soy-Free; Dairy Free; Gluten Free; Contains no listed major allergens in Supplement Facts and other ingredients.

Ingredients explained:
Riboflavin-5'-phosphate (Vitamin B2)
As a coenzyme (FAD/FMNH2), it helps enzymes in energy production and antioxidant recycling in cells.

Caution: High-dose B2 may cause bright yellow urine; this is harmless and due to riboflavin excretion.

Pyridoxal-5'-phosphate (Vitamin B6)
As the active form of B6, it supports amino acid metabolism and neurotransmitter synthesis.

Caution: Large amounts of B6 over time may cause nerve tingling or numbness; follow the suggested use.

5-Methyltetrahydrofolate (Quatrefolic)
As the methylated form of folate, it donates methyl groups for homocysteine metabolism and DNA-related processes.

Caution: Folate can mask low vitamin B12 status; consistent B12 intake is important when using folate.

Methylcobalamin (Vitamin B12)
As a methyl donor and cofactor, it supports homocysteine metabolism and red blood cell formation.

Caution: Very high B12 intakes may cause mild acne-like skin changes in some people; discontinue if bothersome.

Betaine (Trimethylglycine)
Acts as a methyl donor to help convert homocysteine to methionine via the BHMT pathway.

Caution: May cause mild digestive discomfort in some individuals; take with water and assess tolerance.

How they work together
Methylated folate and methylcobalamin provide methyl groups for the methionine cycle, while betaine supports an alternate methylation route via BHMT. Riboflavin-5’-phosphate and pyridoxal-5’-phosphate act as enzyme cofactors that help drive one-carbon and amino acid metabolism, complementing the methyl donors.